AC Milan are looking to extend their advantage over Olympique de Marseille, who are just a point behind in third place, when they face eachother for Wednesday's Group C encounter at the San Siro.
Both sides know that victory would put them a step closer to the last 16.
AC Milan are sweating over the fitness of striker Marco Borriello, who is struggling with a knee injury, ahead of their clash against Marseille.
The Italian forward was the inspiration behind his team's 4-3 triumph against Cagliari at the weekend, scoring a goal and earning a penalty.
That result marked Milans fourth win in five games, keeping Leonardo's side third in the domestic standings, seven points behind Serie A leaders Inter Milan.
A draw would not be a bad result for the hosts considering they take on FC Zurich in Switzerland in the final group match. However, OM will be desperate to claim a win as they face a more challenging game at home to Real Madrid next month.
Didier Deschamps' side travel to the San Siro in good spirits after moving to fourth in Ligue 1 with Friday's 1-0 win over fierce rivals Paris St Germain, courtesy of a Gabriel Heinze goal.
The French giants ended a run of six straight away defeats in the competition with a win at Zurich last on October 21.
The hosts welcome back defender Alessandro Nesta from suspension while they are without injured trio Marek Jankulovski, Gennaro Gattuso and Oguchi Onyewu.
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